Ingredient · dataset v56
Diisostearyl Malate and fungal acne
May trigger · Limited evidence
Why it's a potential trigger
Two isostearyl alcohol halves (ruled trigger-1) on malic acid; the alcohol halves carry the call twice over.
Inheritance call; the malate half is below range.
Evidence strength
Limited evidence (1/3)
Function
Fatty ester
Fatty esters: split by the yeast’s enzymes into edible fats.
Products without this ingredient
- Uriage Thermal Water Spray 300 ml
- Biossance 100% Squalane Oil 3.3 oz
- Mixsoon Glacier Water Ice Soothing Gel 150 ml
- Bye Bye Blemish Original Drying Lotion 1 oz
- Native Body Wash Cucumber & Mint 18 oz
- Eucerin Dermopure Cleansing Gel
Related fatty ester
- Ascorbyl Palmitate — May trigger · Moderate evidence
- Ascorbyl Tetraisopalmitate — May trigger · Moderate evidence
- Behenyl Acrylate — May trigger · Limited evidence
- Behenyl Behenate — May trigger · Limited evidence
- Bis-Octyldodecyl Dimer Dilinoleate/Propanediol Copolymer — May trigger · Moderate evidence
- Butylene Glycol Dicaprylate/Dicaprate — No known trigger
- Butyloctyl Salicylate — May trigger · Limited evidence
- C12-15 Alkyl Benzoate — May trigger · Limited evidence
Sources
- Brunke & Hube 2006 — MfLIP1 extracellular lipase hydrolyses Tweens (Microbiology)
- Mayser et al. 1995 — ester hydrolysis depends on alcohol moiety (Acta Derm Venereol)
- EU CosIng database — search the INCI name
Last reviewed: 2026-10-13 (dataset v56).
Questions
Does Diisostearyl Malate trigger fungal acne?
We flag it as a potential trigger (limited evidence). That means it belongs to a class the Malassezia yeast is known to feed on — not that every product with it will cause a flare. Concentration, formulation and individual skin chemistry matter.
Does Diisostearyl Malate feed Malassezia?
Yes: we flag Diisostearyl Malate as a potential trigger (limited evidence). It belongs to a class Malassezia is known to feed on — not a claim that every product with it causes a flare. Concentration, formulation and individual skin chemistry matter.
How confident is this call?
Limited evidence: Two isostearyl alcohol halves (ruled trigger-1) on malic acid; the alcohol halves carry the call twice over.
Is this medical advice?
No. We screen ingredient lists; we never diagnose, treat, or certify products. When in doubt, ask a dermatologist.
Check a full list containing Diisostearyl Malate →
Not medical advice: we screen ingredient lists for potential triggers — we never diagnose, treat, or certify products. Dataset v56.