Ingredient · dataset v56
Octyldodecyl Neopentanoate and fungal acne
May trigger · Limited evidence
Why it's a potential trigger
Neopentanoic acid (C5) esterified to ruled trigger-1 octyldodecanol (C20); cleavage would free the ruled alcohol, so it inherits trigger-1 under the alcohol-inheritance rule.
Prodrug of a ruled alcohol.
Evidence strength
Limited evidence (1/3)
Function
Fatty ester
Fatty esters: split by the yeast’s enzymes into edible fats.
Products without this ingredient
- SVR [B3] Essence Hydra 150 ml
- Happy Cappy Medicated Shampoo & Body Wash
- Roe Wellness SPF 50 Mineral Powder
- Pyunkang Yul Essence Toner 200 ml
- Cococare Africare 100% Mineral Oil 8.5 fl oz
- Sebamed Clear Face Care Gel 50 ml
Related fatty ester
- Ascorbyl Palmitate — May trigger · Moderate evidence
- Ascorbyl Tetraisopalmitate — May trigger · Moderate evidence
- Behenyl Acrylate — May trigger · Limited evidence
- Behenyl Behenate — May trigger · Limited evidence
- Bis-Octyldodecyl Dimer Dilinoleate/Propanediol Copolymer — May trigger · Moderate evidence
- Butylene Glycol Dicaprylate/Dicaprate — No known trigger
- Butyloctyl Salicylate — May trigger · Limited evidence
- C12-15 Alkyl Benzoate — May trigger · Limited evidence
Sources
EU CosIng database — search the INCI name
Last reviewed: 2026-10-13 (dataset v56).
Questions
Does Octyldodecyl Neopentanoate trigger fungal acne?
We flag it as a potential trigger (limited evidence). That means it belongs to a class the Malassezia yeast is known to feed on — not that every product with it will cause a flare. Concentration, formulation and individual skin chemistry matter.
Does Octyldodecyl Neopentanoate feed Malassezia?
Yes: we flag Octyldodecyl Neopentanoate as a potential trigger (limited evidence). It belongs to a class Malassezia is known to feed on — not a claim that every product with it causes a flare. Concentration, formulation and individual skin chemistry matter.
How confident is this call?
Limited evidence: Neopentanoic acid (C5) esterified to ruled trigger-1 octyldodecanol (C20); cleavage would free the ruled alcohol, so it inherits trigger-1 under the alcohol-inheritance rule.
Is this medical advice?
No. We screen ingredient lists; we never diagnose, treat, or certify products. When in doubt, ask a dermatologist.
Check a full list containing Octyldodecyl Neopentanoate →
Not medical advice: we screen ingredient lists for potential triggers — we never diagnose, treat, or certify products. Dataset v56.